Selected Publications

Decoding functional hematopoietic progenitor cells in the adult human lung

Precision targeting of β-catenin induces tumor reprogramming and immunity in hepatocellular cancers

Identification, Purification and Characterization of Mast Cells in Murine Liver Fibrosis: Novel Methods, Expression Signatures and Correlation with Disease Severity

Spatial map of native duct cell populations in human pancreas and their representation in pancreatic cancers

Brain-wide cell-type-specific transcriptomic signatures of healthy ageing in mice

Cross-species comparison reveals therapeutic vulnerabilities halting glioblastoma progression.

Participation of ventricular trabeculae in neonatal cardiac regeneration leads to ectopic recruitment of Purkinje-like cells

Unravelling cell type-specific responses to Parkinson’s Disease at single cell resolution

Gene regulatory network landscape of Group 3/4 medulloblastoma

Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage

Multimodal decoding of human liver regeneration

The assembly of cancer-specific ribosomes by the lncRNA LISRR suppresses melanoma anti-tumour immunity

Spatial omics of acute myocardial infarction reveals a novel mode of immune cell infiltration

Translatome profiling reveals Itih4 as a novel smooth muscle cell–specific gene in atherosclerosis

Traumatic brain injury promotes neurogenesis at the cost of astrogliogenesis in the adult hippocampus of male mice

Transcriptomic and spatial dissection of human ex vivo right atrial tissue reveals proinflammatory microvascular changes in ischemic heart disease

Identifying Spatial Co-occurrence in Healthy and InflAmed tissues (ISCHIA)

A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma

IL-1β+ macrophages fuel pathogenic inflammation in pancreatic cancer

A spatially resolved single cell genomic atlas of the adult human breast

Single-cell transcriptomics shows dose-dependent disruption of hepatic zonation by TCDD in mice

Identification of astrocyte-driven pseudolineages reveals clinical stratification and therapeutic targets in Glioblastoma

Modelling viral encephalitis caused by herpes simplex virus 1 infection in cerebral organoids

Active eosinophils regulate host defence and immune responses in colitis

Dissecting the polygenic basis of atherosclerosis via disease-associated cell state signatures

Multimodal spatiotemporal phenotyping of human retinal organoid development

Sphere-sequencing unveils local tissue microenvironments at single cell resolution

Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches

A cellular hierarchy in melanoma uncouples growth and metastasis

Single-cell spatial transcriptomics reveals a dynamic control of metabolic zonation and liver regeneration by endothelial cell Wnt2 and Wnt9b